Traumatic Brain Injury | Featured Research

The TRAIN Study: Teaching Risk Reduction in Athletics with Interactive Networking

The TRAIN Study is a three-year CDC-funded study focused on improving communication and education about concussion in middle school sports. The project aims of the study are to: 1) identify the facilitators and barriers to adopting and implementing a Popular Opinion Leader (POL) concussion intervention in middle school football, basketball, and soccer sports communities; 2) determine the effect of a POL intervention on concussion-related behavioral and environmental determinants, including attitudes, beliefs, knowledge, intentions, perceived control, and normative perceptions among parents, coaches, and student-athletes participating in middle school football, basketball, and soccer; and 3) determine the effect of a POL intervention on concussion risk and clinical management through decreased head impact frequency, increased reporting of suspected concussions, changes in concussion incidence, and improved management of confirmed concussions among middle school student-athletes participating in football, basketball, and soccer. The TRAIN study is supported by the CDC National Center for Injury Prevention and Control. PIs: Zachary Y. Kerr, PhD PHH | Johna Register-Mihalik, PhD, ATC

The Active Rehab Study: Role of Active Rehabilitation in Concussion Management: A Randomized Controlled Trial

The Active Rehab Study is a randomized clinical trial that involves high school, collegiate, and professional sports. The overall study goal is to yield initial data on the potential benefits of active rehabilitation during recovery after sport-related concussion (SRC) in professional and amateur athletes. The project goals are to: 1) compare the effects of a multidimensional rehabilitation protocol versus enhanced graded exertion on clinical recovery, return to play, and patient outcomes after SRC; and 2) demonstrate the safety and feasibility of active intervention protocols when introduced during the sub-acute recovery period after SRC, as part of a multidimensional rehabilitation protocol. The Active Rehab Study is funded by the National Football League. PI: Johna Register-Mihalik, PhD, ATC

National Center for Catastrophic Sports Injury Research (in partnership with the Department of Exercise & Sport Science)

The mission of the National Center for Catastrophic Sport Injury Research (NCCSIR) is to conduct surveillance of catastrophic injuries and illnesses related to participation in organized sports in the United States at the collegiate, high school, and youth levels of play. Working through the Consortium for Catastrophic Injury Monitoring, the NCCSIR tracks fatal and severe sports injury cases using a systematic data reporting system that allows for longitudinal investigation of athletes suffering from catastrophic injuries and illnesses. The goal of the Center is to improve the prevention, evaluation, management, and rehabilitation of catastrophic sports-related injuries. The NCCSIR is funded by a variety of sources including: American Football Coaches Association, American Medical Society for Sports Medicine, National Athletic Trainers’ Association, National Collegiate Athletic Association, National Federation of State High School Associations, National Operating Committee on Standards for Athletic Equipment (NOCSAE). PI: Kristen L. Kucera, PhD, ATC


The BANK Study: Beliefs, Attitudes, Norms, & Knowledge

The long-term research mission of the Concussion Disclosure BANK study is to improve concussion prevention, detection, and care by combining training and education with excellence in clinical care. The primary project goal is to develop a theory-driven educational intervention that changes norms and personal beliefs around concussion disclosure. The project is a collaboration between the IPRC and the Keller-Army Hospital at the United States Military Academy and is funded by a Mind Matters Research Challenge Grant from the NCAA-DOD Grand Alliance. PIs: Johna Register-Mihalik, PhD, ATC | Stephen W. Marshall, PhD


Traumatic Brain Injury | Selected Prior Research

The BeMod Study: Innovative Behavior Modification Strategies to Reduce Mild Traumatic Brain Injury in High School Athletes

This study was three-year long prospective, longitudinal, and multi-site investigation with the goal of reducing the risk of concussion in high school football players. The study incorporated advanced telemetry instrumentation to monitor head impact profiles and identify athletes who may benefit from an individualized coaching and mentoring program designed to address key technical deficiencies related to football play. The BeMod Study was funded by the CDC National Center for Injury Prevention and Control. PI: Kevin M. Guskiewicz, PhD, MS, ATC

Prospective Investigation of Sport-Related Concussion: Relationship between Biomechanical, Neuroanatomical, and Clinical Factors

This series of studies aimed to understand the relationships between in-vivo head impact biomechanics, concussion risk, and clinical outcomes. The UNC Matthew Gfeller Center has continued this work over the past 15 years and is internationally known for their work in better understanding head impact biomechanics of sport-related concussion and subconcussive head impacts. This series of studies has been funded by the CDC National Center for Injury Prevention and Control, NOCSAE, and the NFL. PIs: Kevin M. Guskiewicz, PhD, MS, ATC | Jason P. Mihalik, PhD MS, ATC